Fish oil supplementation for Acne

People have tried bizarre home remedies for acne including urine, cow dung etc. Fish oil is not that bizzare but this is probably the first study to report on the effects of fish oil. The study has extremely small patient numbers though and I would not draw any conclusions from this study, as one cannot extrapolate small numbers to the entire population. Further larger studies on this are needed before one can draw any conclusions.

Effects of fish oil supplementation on inflammatory acne.



BACKGROUND: Given that acne is a rare condition in societies with higher consumption of omega-3 (n-3) relative to omega-6 (n-6) fatty acids, supplementation with n-3 may suppress inflammatory cytokine production and thereby reduce acne severity.


13 individuals with inflammatory acne were given three grams of fish oil containing 930 mg of EPA to their unchanged diet and existingacne remedies for 12 weeks. Acne was assessed using an overall severity grading scale, total inflammatory lesion counts, and colorimetry.


There was no significant change in acne grading and inflammatory counts at week 12 compared to baseline. However, there was a broad range of response to the intervention on an individual basis. The results showed that acne severity improved in 8 individuals, worsened in 4, and remained unchanged in 1. Interestingly, among the individuals who showed improvement, 7 were classified as having moderate to severe acne at baseline, while 3 of the 4 whose acne deteriorated were classified as having mild acne.


There is some evidence that fish oil supplementation is associated with an improvement in overall acne severity, especially for individuals with moderate to severe acne. Divergent responses to fish oil in our pilot study indicates that dietary and supplemental lipids are worthy of further investigation in acne.

[PubMed – as supplied by publisher] 


Fish oil supplementation for Acne

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